Abbreviations: DVT, deep vein thrombosis; IL-6, interleukin-6; TNF- α, tumor necrosis factor-α; IL-1β, interleukin-1β; CRP, C-reactive protein; MMP-9, matrix metalloproteinase-9; VEGF, vascular endothelial growth factor; TF, tissue factor; soluble P-selectin (sP-selectin). Here, F3 is linked to deep vein thrombosis.