In addition to cytokines, also MMP-9 production and TF activity were higher in DVT+ cancer patients than in those DVT- and in healthy controls (mean ± SD, 103 ± 23, 73 ± 24, 8.8 ± 4, for MMP-9 and mean ± SD, 35.6 ± 6.4, 28 ± 5, 3.3 ± 0.7 for TF activity, respectively). This evidence concerns the gene TF and cancer.