CDH3 and breast carcinoma: In our previous work, we found that loss of E- and P-cadherin caused defective CICs formation in a group of human breast cancer cells, such as MDA-MB-231, MDA-MB-453 and SKBR3 and the like, re-expression of E- or P-cadherin alone was sufficient to induce entotic CICs in these cells9.