DPP-4 plays a role in fibroblast activation in the liver by activating hepatic stellate cells (Piazza et al. 1989; Levy et al. 1999), while sitagliptin, a DPP-4 inhibitor, attenuates hepatic fibrosis by suppressing activated hepatic stellate cells in rats (Kaji et al. 2014). Here, DPP4 is linked to Hepatic fibrosis.