CMYA5 has been associated with schizophrenia (Wang et al., 2014; Watanabe et al., 2014), depression (Wang et al., 2014) and BD (Nurnberger et al., 2014).CMYA5 interacts with dysbindin (Benson et al., 2004), which has been linked to both schizophrenia and BD (Breen et al., 2006; Joo et al., 2007; Pae et al., 2007). This evidence concerns the gene CMYA5 and depressive symptom measurement.