MTOR and neurodevelopmental disorder: A lot of progress has recently been made in the identification of mutations affecting the rat sarcoma viral oncogene homolog (Ras)/extracellular-signal-regulated kinase (ERK) and the phosphatidylinositol 3-kinase (PI3K)-mammalian target of rapamycin (mTOR) signaling pathways, which are responsible for several neurodevelopmental disorders (Krab et al., 2008).