PARP1 and neoplasm: For assessment ofapoptosis in the tumor cells, cleavage of PARP-1 was analysed byimmunohistochemical method using specific antibody to detect cleaved PARP-1.Cleavage of PARP-1 was found to be at very low levels in the tumor tissues fromvehicle treated mice whereas in the tumor tissues from SQDG treated mice PARP-1cleavage increased to the intermediate levels (Supplementary Table S9), suggesting theinduction of apoptosis in the SQDG treated tumor cells.