The results showed that VTD significantly increases cell detachment of HCT-116 (poorly-differentiated colon cancer cell line, Figure 4A), LoVo (well-differentiated colon cancer cell line, Figure 4B) and U2OS (osteosarcoma with perinuclear mot-2 expression [40, 41], Figure 4C) in a dose-dependent and time-dependent manner. Here, HSPA9 is linked to malignant colon neoplasm.