Measurement of UBXN2A in cells and tissues (Figure 3) confirmed UBXN2A expression increases at least 1.84-fold in colon tissues (1.32-fold in small intestine and no changes in liver) in the presence of Veratrine (Figure 3E) and is increased 2–4 fold by its purified form, VTD, in HCT-116 colon cancer cells (Figure 3G). The gene discussed is UBXN2A; the disease is malignant colon neoplasm.