This hypothesis could be supported by our data collected in the comparison of STCs vs STPs: among the RNAs overexpressed in STCs vs STPs, COL1A1, COL1A2 and COL5A1 are known markers of the mesenchymal glioblastoma subtype, as well as IGFBP6, DCBLD2 and OLFM1, all expressed by microglia or reactive astrocytes [13, 10]. The gene discussed is COL1A1; the disease is glioblastoma.