ID1 and metastatic malignant neoplasm: Some tumor lymphangiogenic inhibitors such as deguelin, endostar, silencing Id-1, liposomal honokiol, mF4-31C1 and sVEGFR3-Ig have been reported as adjuvant antilymphangiogenic and antitumor drugs against some metastatic cancers in experiment and in clinic setting [6, 7, 14, 16, 26, 35, 52].