EGFR and non-small cell lung carcinoma: Ren et al. [24] more recently found that patients with epithelial phenotype responded better to EGFR-TKIs than those with epithelial-to-mesenchymal or mesenchymal phenotype in patients with wild-type EGFR NSCLC in terms of PFS (4.4 versus 1.9 versus 1.0 months, P < 0.001) and OS (11.5 versus 8.9 versus 4.9 months, P < 0.001).