When the gastritis patients were compared with the gastric cancer patients, in the carriers of the rs744166 AA genotype, the frequency of infection with CagA strains with one EPIYA-C segment was significantly higher in the former (p = 0.01; OR = 2.68; 95 % CI = 1.17 – 6.28). The gene discussed is S100A8; the disease is gastric cancer.