ALB and Sepsis: As shown in Table 6, the fluid accumulation in the intracellular compartment was independently associated with in-hospital mortality; however, the fluid accumulation in the extracellular compartment was not an independent predictor of in-hospital mortality when adjustments were made for age, BMI, the presence of sepsis, SOFA score, actual CVVHDF dose, CVVHDF initiation time, PT and serum albumin levels.