To assess the risk factors of HIV-positive women for acquiring HPV infections, we analyzed the CD4/μL (< 200, 200–499, > 500), ARN/HIV copies/mL (< 10,000, 10,000–1,000,000, >100,000), age group, number of sexual partners and smoking in relation to the type of HPV infection (single versus multiple infections). This evidence concerns the gene CD4 and infection.