Moreover, the percentage of people unaware of their HIV positive status, estimated at 40% in 2007 [9], and the proportion of HIV patients with late entry into care (i.e. with CD4 cell count <350/mm3 or an AIDS-defining event regardless of CD4 count, quantified at 43% in 2012) are relatively high in the Netherlands [8] compared to other Western countries [10–12]. The gene discussed is CD4; the disease is AIDS.