Cystic fibrosis (CF), the most common genetic disease in Caucasian populations, results from mutations in a single gene encoding for 1480 residues transmembrane glycoprotein, the cystic fibrosis transmembrane conductance regulator (CFTR), that regulates cAMP-mediated chloride conductance at the apical surface of secretory epithelia [1, 2]. Here, CFTR is linked to cystic fibrosis.