TOM1 and cystic fibrosis: To validate this observation the coexpression of miR-126 and TOM1 was evaluated in CF and non-CF bronchial epithelial samples and cell lines, and a reciprocal expression pattern was evident; the effect of overexpression of miR-126 on TOM1 gene and protein levels was examined in a CF bronchial epithelial cell line, and a miR-126::TOM1 mRNA interaction was functionally validated using a reporter system.