Cho et al. [82] have demonstrated that long-term administration of FA in mice prevented the Aβ(1–42)-induced activation of astrocyte cells, which release free radicals and pro-inflammatory cytokines after Aβ activation, resulting in the inflammatory profile of AD, Furthermore, Yan et al. [83] have studied the effect of FA administration in female APP/PS1 (APPswe/PS1dE9) transgenic mice, which over express the Swedish mutation of APP together with presenilin 1 (PS1) deleted in exon 9. This evidence concerns the gene APP and Alzheimer disease.