Because NESG1 is a tumour-suppressor gene that inhibits cell proliferation, invasion and migration of NPC cells [116], proteins of NESG1-overexpressing NPC 2F4, 3D8 cells and their control of C6 cells were subjected to 2-DE and MALDI-TOF-TOF [94]. This evidence concerns the gene CFAP45 and nasopharyngeal carcinoma.