TP53 and cancer: More specifically, caffeic acid phenylethyl ester (CAPE) (1, Figure 1), a prominent plant phenolic acid, has generated significant attention because of its ability to elicit cancer cell death mainly through the suppression of the cell’s survival pathway (i.e., NFκB) [17,18,19] or concomitant induction of apoptosis cascades (i.e., Bax, p53, etc.) [18,20,21,22].