IL-16 and TNF-α were undetectable in all cell culture supernatants (data not shown), but was secreted in both tumour tissues (IL-16: 5337 ± 33 and 3121 ± 94 pg/ml respectively, TNF-α: 0.30 ± 0.11 and 1.07 ± 0.17 pg/ml respectively). This evidence concerns the gene IL16 and neoplasm.