Notably, in all cervical cancer and CIN specimens, the expression of MKRN1 was positively correlated with the expression of pAKT (Spearman's rho=0.167 (P=0.030) and Spearman's rho=0.411 (P<0.001), respectively), whereas MKRN1 expression was negatively correlated with PTEN expression (Spearman's rho=−0.260 (P=0.001) and Spearman's rho=−0.175 (P=0.002), respectively, Supplementary Table 2). This evidence concerns the gene PTEN and cervical carcinoma.