Histologically, inflammatory hypophysitis is classified into 5 subtypes: lymphocytic, granulamatous, xanthomatous, xanthogranulomatous, and necrotizing.4,5 Hypophysitis can also be classified as idiopathic hypophysitis and secondary hypophysitis which may be caused by systemic inflammatory disorders such as tuberculosis, Wegener's granulomatosis, histiocytosis-X, and sarcoidosis.4,6 The majority of inflammatory pituitary lesions occur in women, are related with the postpartum period, and most of them are in the form of LH.7 Here, PLOD1 is linked to Langerhans cell histiocytosis.