SALL2 and glioblastoma: Evidence have supported a role for Sall2 as a tumor suppressor.3, 12, 13, 50 However, Sall2 is upregulated in various human cancers15, 16, 17, 18, 19, 51 and is essential for glioblastoma propagation.4 These evidences suggest that the role of Sall2 is cell context-dependent.