Transcription factor like nuclear factor κ of activated B cells (NF-κB) [5], pro-inflammatory cytokines such as tumor necrosis factor (TNF) and interleukin 1 (IL 1) [6], toll-like receptors 4 (TLR4) [7] , adiponectin [8] and nuclear hormone receptors [9] are related to inflammatory pathways in DN. The gene discussed is TNF; the disease is liver dysplastic nodule.