NEXN and Familial prostate cancer: In particular, pomegranate juice and a combination of luteolin, punicic acid, and ellagic acid reduced cell migration through the downregulation of several genes such as type I collagen, tenascin C, and chimerin 1 in prostatic cancer cells (PC3) [82], HMMR, collagen type I alpha1 (COL1A1), anillin (ANLN), and nexilin (NEXN) in breast cancer cells (MCF7) [109].