Its antitumorigenic effects were elicited through an inhibition of COX-2, matrix metaloproteinase-9 (MMP-9), and NFκB activation in breast tumor, since the enzymes MMP-9 and COX-2 are involved in the tumor metastasis, and NF-κB mediates tumor cell proliferation [41]. Here, NFKB1 is linked to breast neoplasm.