NFKB1 and coronary artery disorder: Furthermore, short-chain fatty acid of cereal fibre prevents inflammatory response in colonic mucosa by binding to the G-protein coupled receptor and also by blocking transcription factor NF-κB. Similarly consumption of brown and black rice for 4 months was found to exert cardioprotective effect by regulating oxidative stress in individuals with preexisting complications, coronary heart disease (CHD) [72].