Recently, echinoderm microtubule-associated protein-like 4 (EML4)-ALK fusion and vinculin (VCL)-ALK fusion have also been identified in non-small cell lung cancer (NSCLC) [15] and renal cell carcinoma [16], respectively, which has not been described in IMT or EIMS yet. The gene discussed is VCL; the disease is hereditary clear cell renal cell carcinoma.