Therefore, we used multiplex ligation-dependent probe amplification (MLPA) and real-time quantitative PCR (qPCR) to examine the copy-number integrity of this gene in our cohort, but found no evidence for small intragenic deletion of D2HGDH in DLBCL (Supplementary Table 2). This evidence concerns the gene D2HGDH and diffuse large B-cell lymphoma.