APOA1 and myocardial infarction: Both plasma from human myocardial infarction patients known to be positive for anti-ApoA-I autoantibodies and anti-ApoA-IgG from immunized animals have been shown to elicit a dose-dependent release of proinflammatory cytokines from human primary macrophages with an optimal response at 40 μg/ml [12, 15, 19].