LRRK2 and Parkinson disease: The study comprised 18 LRRK2-PD subjects from 17 families (17 patients carrying the G2019S mutation and one the R1414G mutation), 17 NMC from 13 families (11 G2019S, three R1414G and three R1414C), 14 NMNC from nine families (11 relatives of LRRK2-PD patients carrying the G1920S mutation, and three individuals from the same family of a R1441G LRRK2-PD patient), and 19 unrelated IPD patients.