Conversely, subjects both with tumours < = 10 mm in diameter and microcarcinoma (unifocal pT1a) were over-represented among BRAF(-) population: in BRAF(-) tumours there were 47 patients with tumour size to 10 mm (49.5%) vs 39 among BRAF(+) (30.7%, p = 0.03). The gene discussed is BRAF; the disease is neoplasm.