Nemeth et al. noted that neutralizing Abs against TGF-β and BM-MSCs derived from TGF-β1-KO mice eliminated the beneficial effect of BM-MSCs in a mouse model of ragweed-induced asthma, suggesting that BM-MSCs-derived TGF-β1 was responsible for the immunosuppressive effect in asthmatic mice [19]. This evidence concerns the gene TGFB1 and asthma.