CASP3 and diabetes mellitus: In our model, alloxan was administered at gd 8and the VYS samples were collected at gd 15; therefore, the reduction in cellularviability, increased level of activated caspase-3 cells and low cell proliferationconfirmed the deleterious effects of diabetes on the physiology of the VYS andconsequently on embryo/fetus development, even in late pregnancy.