Parameters with asignificant impact on survival after univariate Cox model analysis werePaCO2, inspiratory capacity, age, BMI, predicted percentage ofFEV1, total symptom duration in years, predicted percentage of FVC,FEV1/FVC, PaO2, C-reactive protein level, erythrocytesedimentation rate, radiographic extent of bronchiectasis, and chronic colonizationby P. aeruginosa. This evidence concerns the gene CRP and bronchiectasis.