OXTR and Anxiety: The haplotype GGGTGTC of the SNVs OXTR rs11131149, rs2243370, rs2243369, rs13316193, rs2254298, rs2268493, and rs2268491 was associated with depressive temperament (Kawamura et al., 2010), while in female adolescents, with adverse parental environment, anxiety and depressive symptoms were the most severe in those heterozygous for OXTR rs2254298 (Thompson et al., 2011).