The mechanism most accredited to explain the link between CV-B infection and T1D is a specific tropism of the virus for insulin-secreting islet β cells (11) – that is, mediated by their expression of the specific virus receptor – and a bystander activation of autoreactive T cells by antigens released by β cells after their damage caused by CV-B infection (12). Here, INS is linked to type 1 diabetes mellitus.