NACC1 and in situ carcinoma: Furthermore, as a result of multivariate analysis, a predictive model was produced: the model identified NAC1 LIs (OR [95% CI] 1.18 [1.11–1.28], p < 0.001) and NAC1 IRI (0.78 [0.68–0.86], p < 0.001) as predictive factors associated with CIS/OSCC (Table 3).