ACE and hydrops fetalis: The use of ACE inhibitors after an MI reduce the incidence of HF by 39–46% in those without HF.[13–15] In those intolerant to ACE inhibitors, ARBs are considered a reasonable substitute—but the evidence for ARBs preventing HF in patients with CHD/MI is less clear.[39],[40] While not tested in Stage A HF, metoprolol succinate helps to prevent remodeling in people with Stage B HF, or asymptomatic LV dysfunction.[16] Despite the evidence for preventing HF in those with CHD/MI, only about half are prescribed ACE inhibitors/ARBs or beta-blockers.