There is no earlier report on potential tumor suppressor activity of this gene, but several other members of the myosin-I gene family have been reported as cancer-related genes, including tumor suppressor gene MYO18B in lung, ovarian and colorectal cancer [34] and involvement of MYO1F in chromosomal translocation and gene fusion in infant acute monocytic leukemia [35]. The gene discussed is MYO1F; the disease is colorectal cancer.