Besides, several glucose metabolic enzymes such as aldolase C, triosephosphate isomerase, glyceraldehydes-3-phosphate dehydrogenase, phosphoglycerate kinase 1, phosphoglycerate mutase were consistently elevated in both brain tissues and PBMCs of schizophrenia as described in previous studies [16, 34–37]. This evidence concerns the gene TPI1 and schizophrenia.