About 80% of ARMS are characterized by recurrent translocations, t(2;13)(q35;q14) or t(1;13)(p36;q14), resulting in 2 different fusion transcripts, PAX3-FOXO1 and PAX7-FOXO1 respectively, encoding for proteins that act as aberrant transcription factors [5,6]. This evidence concerns the gene FOXO1 and alveolar rhabdomyosarcoma.