Given that remote ischemic preconditioning (RIPC) has clinical potential to minimize myocardial infarction in patients with high risk [53] and that RIPC mediates protection indirectly via remote humoral conditioning including adenosine, bradykinin, opioids, and HIF but minimal correlation with AT1R [54, 55], the present finding may not suggest the exclusion of RIPC for patients with sartans. This evidence concerns the gene AGTR1 and myocardial infarction.