SOD1 and myocardial ischemia: Through observing the changes in MDA and SOD levels, we can grasp an idea of the dynamic process of free radicals [21].Myocardial ischemia reperfusion and high +Gz stress can lead to abnormal myocardial free radical metabolism, which affect the structure and function of the heart, may increase membrane lipid peroxidation, may cause cell calcium overload and outflow, and may induce mitochondrial damage.