Should they be translated to a diagnostic test, our results suggest that it should be possible to identify babies who are destined develop LO-BSI with a sensitivity of 91% and specificity of 70%, out-performing single CRP measurements in the prediction of late onset sepsis.[41] Our analysis identified significant features both in the composition of the microbiota and a failure to mature—persistent staphylococci and Enterobacteriaceae and paucity of obligate anaerobes—which, whilst not necessarily causal, are correlated with a progression to LO-BSI. The gene discussed is CRP; the disease is Sepsis.