VCP and amyotrophic lateral sclerosis: Recently, the list of degenerative disorders that are associated with VCP mutations has expanded to include amyotrophic lateral sclerosis (ALS) (Abramzon et al., 2012), spastic paraplegia (Clemen et al., 2010), scapuloperoneal muscular dystrophy (Liewluck et al., 2014) and Charcot-Marie-Tooth disease (Gonzalez et al., 2014).