VEGFA and age-related macular degeneration: VEGF-A is known as being directly responsible for wet-form AMD chorioretinal neoangiogenesis, but it also plays a neuroprotective function in retinal nervous structures such as ganglion cell layer (GCC) and nerve fiber layer (RNFL), interacting especially with VEGFR2-receptor that is largely expressed over neuroretina [16–18].