Eleven of the Systemic Lupus International Collaborating Clinics (SLICC) [6] classifications criteria of SLE were met which included (1) malar rash; (2) oral ulcer; (3) nonscarring alopecia; (4) discoid rash; (5) photosensitivity; (6) serositis; (7) arthritis; (8) hematological disorders, anemia; (9) renal disorder, 24-hour urinary protein 2.41 g/L and biopsy proven nephritis; (10) strongly positive ANA; (11) positive anti-dsDNA (>1 : 180 titer). The gene discussed is BTG3; the disease is Arthritis.