Fixed-effects meta-analysis of 1059 CAD cases and 1059 healthy controls suggested that individuals carrying the TT + CT genotypes of MMP-2 -1306 C/T did not have higher or lower risk of CAD (odds ratio: 0.93, 95% confidence interval: 0.78–1.10 under TT + CT vs CC) (see Figure 2). This evidence concerns the gene MMP2 and coronary artery disorder.