We analysed the association between TNF-α-308G > A and clinical characteristics (age at diagnosis, BMI, tumour stage, tumour size, lymph node metastasis, distant metastasis, age at menarche, menopause and family history of cancer) by BC subtypes classified using IHC (Table 4). The gene discussed is TNF; the disease is metastatic malignant neoplasm in the lymph nodes.